1. Long-term central venous catheter device

Patent applied for Brazilian Patent Department in 2006 and at the USPTO in 2007 – Due to confidentiality interest it is not possible to disclose its Applicant Number yet.

Abstract: Stands for an innovative medical device comprising a long-term catheter for cancer chemotherapy. Its main application is focused on the treatment of hematological malignancies such as leukemias, lymphomas, aplastic anemia and myelomas; indicated for those outpatients treated by conventional chemotherapy as well as for those who need bone marrow transplants. The great insight of the invention comes from being free of needle and dressing-aid; and yet, it has a painless-handling and high-flow stream.
Invention-related publication: To be written.

2. Long-term valvular Catheter

Applied in 1984 and Acquired Brazilian Patent INPI # PI8402187,1990.
Abstract: The first tip-valve catheter described in the world. The Brazilian Application Date was 1984. It is indicated for long-term intra-arterial chemotherapy of the liver. At that time the invention came into the market as an option to substitute the expensive totally-implantable infusion pumps. It was put on the market through the company Macchi Engenharia Biomédica Ltda, São Paulo, Brazil, whose folder can be seen here Invention-related publication: Pires e Albuquerque M, Theóphilo FJ. A Valvular Semi-implantável Catheter for long-term chemotherapy treatment: New option to be used in chemotherapy. Rev Bras Cancerol,30(4):54-56,1984.

3. Esophageal Transtumoral endoprosthesis

Application Brazilian Patent INPI # PI8402186, 1984.
Abstract: It was the first flexible endoesophageal prosthesis described in the world. At that time the rigid tubular prostheses were the formats, and something flexible had not been conceived yet. After some years the rigid endoesophageal prostheses were abandoned. It was put on the market through the company Macchi Engenharia Biomédica Ltda, São Paulo, Brazil, whose folder can be seen here Invention-related publication: Pires e Albuquerque M, Dias JA. Treatment of the esophageal tumors: Experience of the Oncology Hospital. Rev Bras Cancerol, 30(2):34-42,1984.